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目的观察辅酶Q10联合阿托伐他汀对冠心病早期心功能减退患者心功能的影响。方法选取医院收治的冠心病早期心功能减退患者110例作为研究对象,随机分为观察组和对照组,每组55例。对照组单独给予阿托伐他汀治疗,观察组给予辅酶Q10联合阿托伐他汀治疗。观察2组患者心功能改善及不良反应发生情况。结果治疗后,2组心功能均得到改善,且观察组改善程度优于对照组(P均<0.05);观察组不良反应发生率为3.63%,低于对照组的16.36%(P<0.05)。结论治疗冠心病早期心功能减退时采用辅酶Q10联合阿托伐他汀治疗具有较高的临床应用价值,患者心功能改善显著,不良反应少。
Objective To investigate the effects of coenzyme Q10 combined with atorvastatin on cardiac function in patients with early hypothyroidism of coronary heart disease. Methods A total of 110 patients with early cardiac dysfunction in coronary heart disease admitted to hospital were selected as study subjects and randomly divided into observation group and control group with 55 cases in each group. The control group was given atorvastatin alone and the observation group was given coenzyme Q10 combined with atorvastatin. The improvement of cardiac function and the incidence of adverse reactions in the two groups were observed. Results After treatment, heart function was improved in both groups and the improvement in the observation group was better than that in the control group (all P <0.05). The incidence of adverse reactions in the observation group was 3.63%, which was lower than that in the control group (16.36%, P <0.05) . Conclusions Coenzyme Q10 combined with atorvastatin has a high clinical value in the treatment of early cardiac dysfunction in patients with coronary heart disease. The patients’ cardiac function is improved remarkably with fewer adverse reactions.