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目的探讨宫颈环形电切术(LEEP)在诊断和治疗宫颈上皮内瘤变中的临床其应用价值。方法采用LEEP对65例宫颈上皮内瘤变患者进行治疗,对其疗效作回顾性分析。结果LEEP手术时间及术中出血量随病变的严重程度增加而增加,手术时间与术中出血量成正相关关系。术前术后病理诊断一致占66.2%;术后病理诊断级别下降占7.7%;术后病理诊断级别上升占26.1%。LEEP治愈率90.8%(59/61),手术时间中位数8.00 min,出血量中位数9.50 ml,术后出血量多5例7.7%(5/65)。结论LEEP为诊断宫颈上皮内瘤变提供可靠的病理标本,只要掌握手术指征,规范手术步骤,注意术后定期追踪随访,可获得满意疗效。
Objective To investigate the clinical value of cervical ring electrosurgical excision (LEEP) in the diagnosis and treatment of cervical intraepithelial neoplasia. Methods 65 cases of cervical intraepithelial neoplasia were treated with LEEP, and its curative effect was analyzed retrospectively. Results LEEP operation time and intraoperative blood loss increased with the severity of the lesion increased, operative time and intraoperative blood loss was positively correlated. Preoperative and postoperative pathological diagnosis consistent accounted for 66.2%; postoperative pathological diagnosis level decreased 7.7%; postoperative pathological diagnosis level increased 26.1%. The cure rate of LEEP was 90.8% (59/61), the median operation time was 8.00 min, the median amount of bleeding was 9.50 ml, and the postoperative bleeding was more serious in 5 cases (7.7%, 5/65). Conclusions LEEP provides a reliable pathological specimen for the diagnosis of cervical intraepithelial neoplasia. As long as the indications of the operation are mastered and the surgical procedures are followed, attention should be paid to the regular follow-up after operation to obtain satisfactory results.