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目的:探讨锌制剂佐治小儿急性腹泻的疗效。方法:将2009年11月～2010年11月吴忠市妇幼保健院收治的6个月～3岁的急性腹泻患儿110例随机分成两组,治疗组58例,对照组52例。两组均采用相同的综合治疗方法,但治疗组同时加用葡萄糖酸锌治疗。结果:治疗组总有效率为91.37%,对照组总有效率为80.76%,治疗组明显高于对照组(P<0.05);治疗组平均止泻时间(3.42±1.58)天,对照组(4.24±2.14)天,治疗组较对照组止泻时间明显缩短(P<0.001);治疗组的临床症状恢复时间较对照组明显缩短(P<0.001)。结论:小儿急性腹泻的患儿在综合治疗基础上加用葡萄糖酸锌口服可有效改善临床症状,减轻病情,缩短腹泻病程,方法简便,疗效满意,值得推广。
Objective: To investigate the curative effect of zinc preparation in treating pediatric acute diarrhea. Methods: From November 2009 to November 2010, 110 children with acute diarrhea of 6 months to 3 years admitted in Wuzhong MCH hospital were randomly divided into two groups: treatment group (58 cases) and control group (52 cases). The same combination therapy was used in both groups, but the treatment group also received zinc gluconate. Results: The total effective rate was 91.37% in the treatment group and 80.76% in the control group, which was significantly higher in the treatment group than in the control group (P <0.05). The average antidiarrheal time was 3.42 ± 1.58 days in the treatment group, ± 2.14) days, the anti-diarrhea time in the treatment group was significantly shorter than that in the control group (P <0.001). The recovery time of clinical symptoms in the treatment group was significantly shorter than that in the control group (P <0.001). Conclusion: Children with acute diarrhea in children on the basis of comprehensive treatment with oral zinc gluconate can effectively improve clinical symptoms, reduce the disease and shorten the course of diarrhea, the method is simple and effective, it is worth promoting.