This paper proposes a multivariable fixed-time leaderfollower formation control method for a group of nonholonomic mobile robots,which has the ability to estimate multiple uncertainties.Firstly,based on the state space model of the leader-follower formation,a multivariable fixed-time formation kinematics controller is designed.Secondly,to overcome uncertainties existing in the nonholonomic mobile robot system,such as load change,friction,extal disturbance,a multivariable fixed-time torque controller based on the fixed-time disturbance observer at the dynamic level is designed.The designed torque controller is cascaded with the formation controller and finally realizes accurate estimation of the uncertain part of the system,the follower tracking of reference velocity and the desired formation of the leader and the follower in a fixed-time.The fixed-time upper bound is completely determined by the controller parameters,which is independent of the initial state of the system.The multivariable fixed-time control theory and the Lyapunov method are adopted to ensure the system stability.Finally,the effectiveness of the proposed algorithm is verified by the experimental simulation.