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再生障碍性贫血(再障)目前尚无特效疗法,用药盲目性较大。尽管骨髓移植和ATG治疗再障的缓解率较高,但花费大,设备及技术条件要求较高,不能作为常规疗法。如何对再障选择最佳治疗方案呢?本文复习近年来有关文献,综述如下: 一、根据临床分型选择治疗方案 1976年Camitta等提出了严重型再障的诊断标准已为多数学者所采用。Camitta等又发现重症再障病人有80%死亡。Pizutto等比较了雄性激素对不同病情再障的疗效,发现重型13例中仅1例(7.7%)有效,轻型65例中30例(46.15%)有效,两组之间有明显差异(P<
Aplastic anemia (aplastic anemia) there is no specific treatment, medication blindness. Although bone marrow transplantation and ATG treatment of aplastic anemia, high remission rate, but the cost, equipment and technical conditions require higher, not as a routine treatment. How to choose the best treatment for aplastic anemia? This review of the literature in recent years, are summarized as follows: First, select the treatment based on clinical classification program 1976 Camitta et al proposed a diagnostic criteria for severe aplastic anemia has been used by most scholars. Camitta and others found that 80% of critically ill patients with aplastic anemia died. Pizutto et al compared the effects of androgens on various stages of aplastic anemia and found that only 1 (7.7%) was effective in 13 cases of severe form and 30 (46.15%) of 65 cases were effective, with significant difference between the two groups (P <