抑素类(Chalones)是一些具有组织特异性、非种属特异性的调节物质,产生于某些组织,并能使该组织的细胞增殖受到抑制。据文献报导,大约有12～13个不同的抑素系统,粒细胞抑素是其中之一。粒细胞抑素存在于血清和粒细胞系统的成熟和幼稚细胞中,并在这些细胞内合成。将粒细胞置于盐液中孵育1～2小时,取其上清液进行超滤和葡聚糖胶滤,即可得到颇为纯净的粒细胞抑素。 Chalones are tissue-specific, non-species-specific regulatory substances that are produced in certain tissues and can inhibit cell proliferation in that tissue. According to reports in the literature, there are about 12 to 13 different somatostatin systems, one of which is cytostatin. Granustatin is present in the mature and immature cells of the serum and granulocyte system and is synthesized in these cells. The granulocytes were incubated in saline for 1 to 2 hours. Supernatant and dextran gel filtration were performed on the supernatants to obtain pure granulostatin.