足叶乙甙为一半合成的鬼臼酯素衍生物,具有广谱的抗肿瘤活性,其作用机制为抑制核苷转移,抑制DNA、RNA及蛋白质的合成。主要用于急性单核细胞型和粒单核细胞型白血病,小细胞肺癌,非何杰金氏恶性淋巴瘤、睾丸癌等。其主要副作用可出现骨髓抑制,白细胞减少、脱发、胃肠道反应如恶心、呕吐等。目前尚无因使用此药引起发热的报道。我院一例急性粒单核细胞型白血病患者,使 Etoposide is a synthetic haloposide derivative with broad spectrum of antitumor activity. Its mechanism of action is to inhibit nucleoside transfer and inhibit DNA, RNA and protein synthesis. Mainly used for acute monocytic and myelomonocytic leukemia, small cell lung cancer, non-Hodgkin’s lymphoma, testicular cancer. The main side effects can occur myelosuppression, leukopenia, hair loss, gastrointestinal reactions such as nausea, vomiting and so on. There are currently no reports of fever caused by the use of this medicine. A case of acute myelomonocytic leukemia in our hospital