一般认为胼胝体变性是由慢性乙醇中毒引起的一种罕见的神经系统并发症,又称Marchiafava—Bignami disease(MBD)。本病于1903年由Marchiafava及Bignami两位病理学家进行详细表述并命名。我国学者在1994年首次报道。MBD患者以出现选择性的胼胝体部位对称性脱髓鞘为其病理特征,而临床表现方面则缺乏特异性,以往诊断主要 It is generally believed that corpus callosum degeneration is a rare neurological complication caused by chronic alcoholism, also known as Marchiafava-Bignami disease (MBD). The disease in 1903 by Marchiafava and Bignami two pathologists in detail and named. Our scholar first reported in 1994. MBD patients with selective symmetry of the corpus callosum site demyelination for its pathological features, but the clinical manifestations of the lack of specificity, the previous diagnosis of the main