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为观察首都医科大学附属北京妇产医院新生儿重症监护室(neonatal intensive care unit,NICU)患儿主要定植细菌及其抗生素耐药情况,以便采取相应措施及时控制医院内感染,本研究选择2014年8月1日—2015年5月31日住院患儿的咽试子标本进行细菌培养,同时进行耐药性分析。677例新生儿咽拭子培养结果显示,230例阳性(34.0%),其中革兰阳性球菌159例(69.1%),革兰阴性杆菌71例(30.9%)。定植细菌中,革兰阳性球菌主要为草绿色链球菌、克氏库克菌及表皮葡萄球菌,革兰阴性杆菌主要为大肠埃希菌、鲍曼不动杆菌及肺炎克雷伯菌。各细菌对常用抗生素的耐药率不同,同时进行药敏试验有助于指导临床用药。
To observe the main bacteria and their antibiotic resistance in neonatal intensive care unit (NICU) of Beijing Maternity and Affiliated Hospital of Capital University of Medical Sciences in order to take appropriate measures to control nosocomial infections in time, this study chose 2014 August 1 - May 31, 2015 inpatients with pharyngeal specimens for bacterial culture, resistance analysis at the same time. Throat swabs from 677 newborns showed 230 positive cases (34.0%), of which 159 (69.1%) were Gram-positive cocci and 71 (30.9%) were Gram-negative bacilli. Gram-positive bacteria, Gram-positive cocci mainly Streptococcus viridans, Cook’s bacteria and Staphylococcus epidermidis, Gram-negative bacteria mainly Escherichia coli, Acinetobacter baumannii and Klebsiella pneumoniae. The rate of resistance of different bacteria to commonly used antibiotics is different, and the drug susceptibility test at the same time is helpful to guide the clinical medication.