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[目的]观察中西医结合治疗病毒性肝炎肝纤维化的临床疗效。[方法]随机将126例慢性病毒性肝炎肝纤维化患者分为2组,各63例,对照组用甘利欣加肌苷片治疗,治疗组用甘利欣加肌苷片加中药治疗,疗程均6个月。观察超声肝脏形态学变化,检测肝功能和肝纤维化指标。[结果]治疗组总有效率为85.7%,优于对照组的71.4%(P<0.05);肝脏形态学超声参数积分的变化、肝功能的改善及肝纤维化指标的变化均明显优于对照组(P<0.05,<0.01)。[结论]中西医结合治疗病毒性肝炎肝纤维化的疗效优于单纯西药护肝治疗。
[Objective] To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of viral hepatitis with liver fibrosis. [Methods] 126 patients with chronic viral hepatitis and liver fibrosis were randomly divided into two groups, 63 in each. The control group was treated with melilixin and inosine tablets. The patients in the treatment group were treated with Ganlixin plus inosine tablets and Chinese herbs for 6 and 6 weeks respectively Months. Ultrasound liver morphological changes observed, detection of liver function and liver fibrosis indicators. [Results] The total effective rate in the treatment group was 85.7%, which was significantly better than that in the control group (71.4%, P <0.05). The change of integral of liver morphology parameters, liver function and liver fibrosis were significantly better than the control Group (P <0.05, <0.01). [Conclusion] The curative effect of combining traditional Chinese and western medicine in the treatment of viral hepatitis with liver fibrosis is better than that with western medicine alone.