论文部分内容阅读
目的分析酒精性肝硬化与肝癌的关系。方法选取医院收治的酒精性肝硬化患者61例,同期收治的乙肝肝硬化患者43例,免疫性肝硬化患者21例及肝癌患者36例,对比不同类型肝硬化患者及肝癌患者的肝功能指标。回顾性分析医院收治的109例肝癌患者原发肝部疾病构成比例。结果酒精性肝硬化与乙肝肝硬化、免疫性肝硬化及肝癌患者的肝功能指标比较,差异均有统计学意义(P<0.01),其中免疫性肝硬化肝功能指标与肝癌较为接近。109例肝癌患者免疫性肝硬化进展为肝癌的占比最高为42.20%,与酒精性肝硬化比较,差异有统计学意义(P<0.01);酒精性肝硬化进展为肝癌的比例高于无肝癌疾病及急性肝炎患者(P<0.01);急性肝炎进展为肝癌与酒精性肝硬化比较,差异有统计学意义(P<0.05);肝炎性肝硬化进展为肝癌的比例与酒精性肝硬化比较,差异无统计学意义(P>0.05)。结论酒精性肝硬化进展为肝癌具有较高的危险性,但其危险性低于免疫性肝硬化患者,与肝炎性肝硬化基本持平,应引起临床给予足够关注。
Objective To analyze the relationship between alcoholic cirrhosis and liver cancer. Methods Totally 61 patients with alcoholic liver cirrhosis admitted in hospital were enrolled, 43 patients with hepatitis B cirrhosis, 21 patients with immune cirrhosis and 36 patients with liver cancer were enrolled in the same period. The liver function indexes of patients with different types of liver cirrhosis and liver cancer were compared. Retrospective analysis of the hospital admitted 109 cases of primary liver cancer patients with liver disease composition ratio. Results There were significant differences in liver function between alcoholic cirrhosis and hepatitis B cirrhosis, autoimmune cirrhosis and liver cancer (P <0.01), and the liver function of immune cirrhosis was similar to that of liver cancer. The highest proportion of 109 cases of HCC patients with liver cancer was 42.20%, which was significantly different from that of alcoholic cirrhosis (P <0.01). The proportion of patients with HCC was higher than that without HCC Disease and acute hepatitis (P <0.01). The progress of acute hepatitis was compared with that of alcoholic cirrhosis (P <0.05). Compared with alcoholic liver cirrhosis, The difference was not statistically significant (P> 0.05). Conclusions The progression of alcoholic cirrhosis to hepatocellular carcinoma is of high risk, but its risk is lower than that of patients with immune cirrhosis, which is basically the same as that of hepatic cirrhosis and should be given sufficient attention in clinical practice.