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本文最初发表于《Nature Genetics》杂志2015年第47卷,题录为:Jiang L,Gu ZH,Yan ZX,Zhao X,et al.Exome sequencing identifies somatic mutations of DDX3X in natural killer/T-cell lymphoma[J].Nat Genet,2015,47:1061-1066。这是迄今为止NK/T细胞淋巴瘤最全面系统的基因组学图谱,也是对相关突变基因致病原理及其临床意义进行的深入系统阐述,反映了我国血液学工作者在淋巴瘤研究中的最高水平,有较重要的理论与临床意义。本文经通信作者的许可,再次通过佳文解读的方式对这一研究成果进行阐述,供各位赏析。
This article was originally published in Nature Genetics, Vol. 47, 2015, titled: Jiang L, Gu ZH, Yan ZX, Zhao X, et al. Exome sequencing identifies somatic mutations of DDX3X in natural killer / T-cell lymphoma [ J]. Nat Genet, 2015, 47: 1061-1066. This is by far the most comprehensive and systematic genomic mapping of NK / T-cell lymphoma and an in-depth systematic exposition of the pathogenesis and clinical significance of the related mutated genes. It reflects that hematology workers in our country have the highest level of research in lymphoma Level, there is more important theoretical and clinical significance. This article, with the permission of the author of the correspondence, elaborates the research results again through the way of reading the texts for your appreciation.