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目的探讨5区13针法和6针法前列腺穿刺活检诊断前列腺癌的差异。方法本组214例,因前列腺特异性抗原>4.0ng/ml或直肠指诊前列腺癌阳性可疑而行13针前列腺穿刺活检术,其中前列腺特异性抗原>4.0ng/ml者203例,直肠指诊前列腺癌阳性可疑者41例。入选病例的年龄为50 ̄90岁,平均69.8岁;PSA水平0.8 ̄112.3ng/ml,平均18.7ng/ml;前列腺体积12.3 ̄182.5ml,平均61.3ml;直肠指诊阴性者173例,阳性者41例。结果6针法和13针法的阳性率分别为30.8(%66/214)和36.0(%77/214),后者的阳性率提高14.3(%11/77()P<0.001)。两者的差异在前列腺特异性抗原≤20ng/ml,指诊阴性,体积>40ml,前列腺特异性抗原密度≤0.30,年龄<70岁的患者中更显著。结论5区13针前列腺穿刺活检术比系统6针发现前列腺癌的阳性率更高。
Objective To investigate the differences between the 13-acupuncture of 5-zone and the 6-prostatic needle biopsy in the diagnosis of prostate cancer. Methods A total of 214 patients undergoing prostate biopsy underwent prostate biopsy with prostate specific antigen> 4.0ng / ml or rectal fingerprinting positive for prostate cancer, including 203 with prostate-specific antigen> 4.0ng / ml, 41 cases of positive prostate cancer suspicious. The age of selected cases was 50 to 90 years old, with an average of 69.8 years; PSA level 0.8 ~ 112.3ng / ml, an average of 18.7ng / ml; prostate volume 12.3 ~ 182.5ml, an average of 61.3ml; 41 cases. Results The positive rates of 6 - and 13 - acupuncture were 30.8% and 66.0%, respectively. The positive rate of the latter was 14.3% (P <0.001). The difference between the two is more pronounced in patients with prostate-specific antigen ≤ 20 ng / ml, finger-negative, volume> 40 ml, prostate-specific antigen density ≤ 0.30, and age <70 years. Conclusions The positive rate of prostate cancer in the 5-zone 13-pin prostate biopsy is higher than that of the 6-needle system.