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目的探讨影响直肠癌术后复发的因素,以便采取相应的措施来减少复发,提高患者的存活率。方法对1992年4月至2004年4月我院直肠癌手术切除的病例291例,应用寿命表法和Kaplan-Meier法进行复发因素分析,采用Log-RankTest和Cox比例风险模型对影响复发的有关因素进行单因素分析和多因素分析。结果复发146例,未复发145例。1年复发率23.04%,3年复发率44.60%,5年复发率50.79%,10年复发率55.09%。影响患者术后复发的主要因素包括年龄、性别、浸润深度和病理分期。结论年龄、性别、浸润深度和病理分期是影响术后复发的主要因素。
Objective To explore the factors that influence the postoperative recurrence of rectal cancer in order to take appropriate measures to reduce the recurrence and improve the survival rate of patients. Methods 291 cases of resected rectal cancer in our hospital from April 1992 to April 2004 were retrospectively analyzed by life table method and Kaplan-Meier method. Log-Rank Test and Cox proportional hazards models were used to evaluate the relapse-related effects Factors for univariate and multivariate analysis. The results of recurrence in 146 cases, 145 cases did not relapse. One-year recurrence rate was 23.04%, three-year recurrence rate was 44.60%, five-year recurrence rate was 50.79%, and the 10-year recurrence rate was 55.09%. The main factors influencing the postoperative recurrence of patients include age, gender, depth of invasion and pathological stage. Conclusion Age, gender, depth of invasion and pathological staging are the main factors affecting postoperative recurrence.