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目的观察长春西汀治疗急性脑梗死的临床疗效及安全性。方法将101例急性脑梗死患者随机分为两组,对照组50例采用常规治疗,治疗组51例在常规治疗基础上加用长春西汀。评价治疗前后神经功能缺损评分的变化及疗效,监测用药前后脑出血等并发症的发生情况及凝血功能、肝肾功能的变化。结果治疗组神经功能缺损评分改善较对照组明显(P<0.05),治疗组总有效率高于对照组(P<0.05)。两组梗死后出血等发生情况无明显性差异。结论长春西汀治疗急性脑梗死安全有效。
Objective To observe the clinical efficacy and safety of vinpocetine in the treatment of acute cerebral infarction. Methods A total of 101 acute cerebral infarction patients were randomly divided into two groups. The control group (n = 50) received routine treatment. The treatment group (n = 51) was treated with vinpocetine on the basis of routine treatment. Evaluation of changes in neurological deficit scores before and after treatment and efficacy, monitoring of complications such as cerebral hemorrhage before and after treatment and coagulation, liver and kidney function changes. Results The improvement of neurological deficit score in treatment group was more obvious than that in control group (P <0.05). The total effective rate in treatment group was higher than that in control group (P <0.05). There was no significant difference in the occurrence of bleeding after infarction in both groups. Conclusion Vinpocetine is safe and effective in the treatment of acute cerebral infarction.