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目的:探讨和分析对糖尿病患者在做肾功能检测时关注血清胱抑素C的重要作用和价值。方法:选取本院自2016年3月至2017年2月期间门诊或者住院的糖尿病患者291例,将其分为单纯糖尿病组、Ⅲ期糖尿病肾病组。同时,以同期健康体检者170例定成对照组,统计和的具体的检测情况。结果:经过检测,结果显示Ⅲ期糖尿病肾病组的Cys-C值为(1.29±0.57)mg/L,显著高于对照组;该两组患者上述指标对比,具有显著差异(P<0.05),存在统计学意义。结论:对糖尿病患者进行的肾功能测定,有力证实了血清Cys-C测定是可以早期发现肾功能实际受损状况的可靠性指标之一,适合于用作评估糖尿病、以及糖尿病肾病患者的早期肾功能的评价。
Objective: To investigate and analyze the important role and value of serum cystatin C in diabetic patients during renal function tests. Methods: A total of 291 outpatients or hospitalized patients with diabetes were selected from March 2016 to February 2017 in our hospital. Patients were divided into simple diabetic group and stage Ⅲ diabetic nephropathy group. At the same time, with the same period of 170 healthy subjects as a control group, the statistics and the specific detection. Results: The results showed that the Cys-C value of diabetic nephropathy group was (1.29 ± 0.57) mg / L, which was significantly higher than that of the control group. There was significant difference between the two groups (P <0.05) There is statistical significance. CONCLUSIONS: The renal function test in diabetic patients strongly supports that the determination of serum Cys-C is one of the reliable indicators of early detection of actual impairment of renal function and is suitable for the assessment of early stage renal disease in patients with diabetes and diabetic nephropathy Functional evaluation.