细胞松弛菌素(Cytochalasin)是一类真菌的代谢产物。自Carter 1967年首次报道以来,迄今已发现有10余种。细胞松弛菌素具有广泛的细胞生物效应。诸如能专一性地作用于哺乳类动物细胞微丝系统,影响细胞的运动。抑制细胞质的分裂而不影响核的分裂,致使形成双核及多核细胞。此外,它还可以引起细胞产生排核现象,调节质膜与植物凝集素的反应等。晚近,不少实验室又把细胞松弛菌素与离心术结合起来,获得去核细胞及 Cytochalasin is a metabolite of a class of fungi. Since Carter first reported in 1967, so far, more than 10 species have been found. Cytosolicins have a broad cellular biological effect. Such as acting specifically on the microfilament system of mammalian cells, affecting the movement of cells. Inhibition of cytoplasmic division without affecting the nuclear division, resulting in the formation of dual-core and multi-nuclear cells. In addition, it can cause cells to produce nuclear excretion, regulate plasma membrane and lectin reaction. Recently, many laboratories in turn cytosolic cytokinin and centrifugation combined to obtain enucleated cells and