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目的了解夫妻间HIV性传播率和影响因素,为制定防治措施提供科学依据。方法采用回顾性研究方法,选择有稳定婚姻的HIV感染者/病人及其配偶作为调查对象。结果 HIV夫妻间传播率为30.0%(39/130),男传女性传播率为33.78%(25/74),女传男性传播率为25.0%(14/56)。单因素分析显示:夫妻性行为频次(χ2=19.433,P=0.000)、夫妻任一方性病史(χ2=4.288,P=0.038)是夫妻间HIV性传播的影响因素。双阳组先证病例确证时CD4细胞计数均值低于单阳组(t=-2.47,P=0.015),感染与确证时间间隔长于单阳组(t=2.507,P=0.013)。多因素分析显示:先证病例性别、确证时年龄、夫妻性生活频次、感染与确证时间间隔是HIV夫妻间性传播的独立影响因素。结论六安市HIV夫妻传播率较高,与先证病例性别、确证时年龄、夫妻性生活频次、感染时间与HIV抗体阳性确证时间间隔等因素有关。
Objective To understand the rate of sexual transmission of HIV between husband and wife and its influencing factors so as to provide a scientific basis for making prevention and control measures. Methods A retrospective study was conducted to select HIV-infected persons / patients with stable marriage and their spouses as the survey subjects. Results The rate of HIV transmission among couples was 30.0% (39/130). The male transmission rate was 33.78% (25/74) and the female transmission rate was 25.0% (14/56). Univariate analysis showed that the frequency of marital sexual behaviors (χ2 = 19.433, P = 0.000) and the history of any sexual partners (χ2 = 4.288, P = 0.038) were the influencing factors of HIV transmission among couples. The mean of CD4 count in confirmed positive cases of Shuangyang group was lower than that in single positive group (t = -2.47, P = 0.015). The interval between infection and confirmation was longer than that in single positive group (t = 2.507, P = 0.013). Multivariate analysis showed that gender, age at confirmation, sex life time of husband and wife, time interval of infection and confirmation were independent influencing factors of sexual transmission among HIV couples. Conclusions The HIV transmission rate among HIV patients in Lu’an City is relatively high, which is related to the gender, age at confirmation, sex life time of husband and wife, time of infection and confirmation interval of HIV antibody positive.