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分析84例原发性多发性癌肿的临床、治疗和预后及其意义。回顾性统计84例原发性多发性癌肿的临床、治疗、预后等相关资料。第一原发癌发生于消化道占42.84%,乳腺占28.57%,呼吸道和甲状腺各占10.72%,其它占7.15%。经过手术、手术+放疗、放疗、手术+化疗和综合治疗等处理,平均间隔5.2年,于同一系统或不同系统又出现第二个原发性癌肿。再经积极治疗,三年内死亡率为47.37%,五年以上存活率为19.74%。原发性多发性癌肿病因复杂,发生于消化道可能与机体易感性等有关;发生于乳腺者认为与激素和遗传因子有一定关系;颌面部原发性癌肿经放疗后,第二原发癌肿仍在颌面部者,证明放射线是一种致癌因素。原发性多发性癌肿如能及时发现,积极治疗,预后将会更好。
The clinical, treatment and prognosis of 84 cases of primary multiple cancers were analyzed. Retrospective statistics on the clinical, treatment, prognosis, and other relevant data of 84 cases of primary multiple cancers. The first primary cancer occurred in 42.84% of the digestive tract, 28.57% of the breast, 10.72% of the respiratory tract and thyroid, and 7.15% of the others. After surgery, surgery + radiotherapy, radiotherapy, surgery + chemotherapy and comprehensive treatment, the average interval of 5.2 years, in the same system or different systems and the emergence of a second primary cancer. After active treatment, the mortality rate was 47.37% in three years and the survival rate was 19.74% in more than five years. The etiology of primary multiple cancers is complex, which occurs in the digestive tract and may be related to the susceptibility of the body; the occurrence of breast cancer is considered to have a certain relationship with hormones and genetic factors; the primary cancer of the maxillofacial region is treated by radiotherapy, and the second The primary cancer is still in the maxillofacial region, proving that radiation is a carcinogenic factor. If multiple primary cancers can be found in time, aggressive treatment, the prognosis will be better.