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细胞周期蛋白 (cyclin)是细胞有丝分裂过程中的一组重要蛋白 ,是细胞周期调节因子之一 ,通过相应的周期素依赖性激酶 (cyclin dependentkinase,CDK)及其抑制因子 (cyclin dependentkinasesinhibitor,CKI)对细胞周期中G1/S期起重要调控作用[1] 。正常细胞中cyclin的合成和降解受
Cyclin is a group of important proteins in cell mitosis. It is one of the cell cycle regulators. Through the corresponding cyclin dependent kinase (CDK) and its cyclin dependent kinase inhibitors (CKI) G1 / S phase in the cell cycle plays an important regulatory role [1]. The synthesis and degradation of cyclin in normal cells are regulated by