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目的 探索螨过敏性哮喘患者一年四季居室内尘螨密度与哮喘发病的关系。方法 对43例螨浸液皮试阳性的哮喘患者 ,每季度采集其卧室中床垫、被褥、沙发和枕头等处的积尘 ,用解剖显微镜计数尘螨 ,同时由患者逐日记录哮喘发作状况、早晚呼气峰流速值和用药情况等。结果 居室一年四季间尘螨密度差异有显著性 (P <0 .0 5 )。秋季尘螨密度最高 [秋季 (149.93± 83 .11)N/ 0 .2 5m2 ,春季 (4 5 .6 4± 2 8.5 0 )N/ 0 .2 5m2 ,夏季 (6 5 .2 5± 2 3.41)N/ 0 .2 5m2 ,冬季 (8.11± 3 .5 6 )N/ 0 .2 5m2 ],且秋季哮喘发作次数较频 ,峰流速较低 ,用药品种较多 ,与其他季节相比差异有显著性 (P <0 .0 5 )。结论 螨过敏性哮喘患者卧室中尘螨密度与哮喘发病有关 ,控制尘螨孳生有可能减轻或控制哮喘发作。
Objective To explore the relationship between indoor dust mite density and the incidence of asthma in mite allergic asthma patients all year round. Methods A total of 43 cases of asthmatic patients with mite immersion skin test were collected on a quarterly basis for dust accumulation in mattresses, bedding, sofas and pillows in their bedrooms. The dust mites were counted with a dissecting microscope and the patients were recorded daily for asthma attacks. Morning and evening peak expiratory flow rate and medication and so on. Results There was a significant difference in the density of house dust mites in all four seasons (P <0.05). The density of autumn mites was the highest in autumn (149.93 ± 83.11) N / 0.225m2, spring (45.4 ± 2 8.5 0) N / 0.225m2, summer (65.2 ± 2 3.41 ) N / 0. 2 5m2, winter (8.11 ± 3.56) N / 0. 2 5m2], and the frequency of autumn asthma attack was relatively low, the peak flow rate is low, the drug variety is more, compared with the other seasons Significance (P <0.05). Conclusion The density of dust mite in the bedroom of mite allergic asthma is related to the pathogenesis of asthma. Controlling the mite breeding may reduce or control the asthma attack.