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目的观察血糖控制及钙尔奇D对男性2型糖尿病患者骨密度及骨钙素(osteocalcin,BGP)的影响。方法随机将107例2型糖尿病患者分为钙尔奇D组55例及对照组52例,控制血糖后再按血糖控制是否达标分亚组,比较患者治疗前后骨密度及骨钙素变化。结果血糖达标组骨密度及骨钙素较未达标组明显改善(P<0.05)。结论良好的血糖控制可改善2型糖尿病患者骨密度,同时服用钙尔奇D疗效更显著。
Objective To observe the effects of glycemic control and Calcium D on bone mineral density and osteocalcin (BGP) in male patients with type 2 diabetes mellitus. Methods A total of 107 patients with type 2 diabetes were divided randomly into 55 patients with type 2 diabetes mellitus and 52 patients with control group. After controlling for blood glucose, patients were divided into subgroups according to their glycemic control. The changes of bone mineral density and osteocalcin before and after treatment were compared. Results Compared with the control group, the BMD and osteocalcin in BG group were significantly improved (P <0.05). Conclusion Good glycemic control can improve BMD in patients with type 2 diabetes, while taking Calcium D significantly more.