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目的探讨盆腔子宫内膜异位症术后辅以孕三烯酮治疗的疗效和不良反应。方法选择子宫内膜异位症患者86例,分为治疗组和对照组,治疗组术后服用孕三烯酮,对照组术后不用药,观察两组疗效。结果治疗组总有效率88.37%,对照组总有效率为60.47%,治疗组的总有效率与对照组相比差异有统计学意义(P<0.05)。治疗组不良反应主要为体重轻度增加、痤疮、不规则阴道流血和肝酶轻度升高,停药及保肝治疗后肝功能恢复正常。结论孕三烯酮辅助治疗治疗子宫内膜异位症,具有不良反应小,可以降低术后复发率,同时提高了受孕率。
Objective To investigate the efficacy and adverse reactions of gestrinone treatment after pelvic endometriosis. Methods Eighty-six patients with endometriosis were divided into treatment group and control group. The treatment group was given gestrinone after operation, and the control group was given no medication after operation. The curative effect of the two groups was observed. Results The total effective rate was 88.37% in the treatment group and 60.47% in the control group. The total effective rate in the treatment group was significantly different from that in the control group (P <0.05). Adverse reactions in the treatment group were mainly mild body weight increase, acne, irregular vaginal bleeding and slight increase of liver enzymes, and liver function returned to normal after treatment and liver protection. Conclusions Gestrinone adjuvant treatment of endometriosis with adverse reactions is small, can reduce postoperative recurrence rate, while increasing the rate of pregnancy.