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目的探讨新生儿缺血缺氧性脑病影响因素,为及时有效治疗提供依据。方法选取2010年4月至2014年8月商丘市妇幼保健院诊治的100例缺血缺氧性脑病新生儿资料,设为实验组,选取同期诊治的100例健康新生儿作为对照组,采取自拟问卷调查表对新生儿相关资料进行统计,分析新生儿缺血缺氧性脑病的影响因素,为新生儿缺血缺氧性脑病治疗提供依据。结果新生儿缺血缺氧性脑病和分娩方式、羊水是否污染、胎盘是否正常,产程是否正常,母体贫血程度高低以及新生儿体重等关系密切(P<0.05);多因素Logistics回归分析可以看出:羊水污染、产程异常、妊娠高血压疾病、胎盘异常、脐带异常以及母体贫血均为新生儿缺血缺氧性脑病影响因素(P<0.05)。结论新生儿缺血缺氧性脑病影响因素较多,相关部门应该做好围生期孕妇自我保健,完善产前检查,降低新生儿缺血缺氧性脑病发生率。
Objective To explore the influencing factors of neonatal hypoxic-ischemic encephalopathy and provide the basis for timely and effective treatment. Methods A total of 100 neonates with hypoxic-ischemic encephalopathy diagnosed and treated in Shangqiu Maternal and Child Health Hospital from April 2010 to August 2014 were selected as the experimental group. One hundred healthy newborns diagnosed and treated at the same period were selected as the control group, The questionnaire is to be used for statistics of neonatal related data to analyze the influencing factors of neonatal hypoxic-ischemic encephalopathy and provide basis for the treatment of neonatal hypoxic-ischemic encephalopathy. Results There was a close relationship between neonatal hypoxic-ischemic encephalopathy and mode of delivery, amniotic fluid contamination, placenta, birth process, maternal anemia and neonatal body weight (P <0.05). Multi-factor Logistic regression analysis showed that : Amniotic fluid pollution, labor abnormalities, pregnancy-induced hypertension, placental abnormalities, cord abnormalities and maternal anemia are the influencing factors of neonatal hypoxic-ischemic encephalopathy (P <0.05). Conclusion There are many influencing factors of neonatal hypoxic-ischemic encephalopathy. Relevant departments should improve the self-care of pregnant women during perinatal period, perfect the prenatal examination and reduce the incidence of neonatal hypoxic-ischemic encephalopathy.