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目的:观察愈美颗粒治疗小儿急性支气管炎的临床疗效及安全性。方法:156例急性支气管炎患儿随机分为两组,对照组予常规抗感染及雾化吸入等治疗,观察组加用愈美颗粒治疗。比较两组患儿咳嗽、咳痰和痰液黏稠度等临床症状改善率和总有效率,并观察药品不良反应。结果:观察组治疗后临床症状评分显著优于对照组(P<0.05)。观察组临床控制率52.56%,总有效率89.74%,均明显高于对照组(P<0.05),且未发生明显药品不良反应。结论:愈美颗粒能有效辅助治疗小儿息性支气管炎,安全性好,值得临床推广使用。
Objective: To observe the clinical efficacy and safety of Yumei Granule in treating children with acute bronchitis. Methods: One hundred and fifty-five children with acute bronchitis were randomly divided into two groups. The control group was treated with routine anti-infective and nebulized inhalation. The observation group was treated with Yumei Granule. The improvement rate and total effective rate of clinical symptoms such as cough, expectoration of sputum and sputum in the two groups were compared, and adverse drug reactions were observed. Results: The scores of clinical symptoms in observation group were significantly better than those in control group (P <0.05). The clinical control rate in the observation group was 52.56%, the total effective rate was 89.74%, which was significantly higher than that in the control group (P <0.05), and no obvious adverse drug reaction occurred. Conclusion: Jumei granule can effectively treat children with infantile bronchitis, which is safe and worthy of clinical application.