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目的监测医院使用环氧乙烷(EO)灭菌时周围环境及其灭菌物品中的EO残留量,并评估其危害。方法采用3M EO气体采样盒,在灭菌过程中采集环境及物品中残留的EO,用气相色谱法测定。结果在灭菌过程中灭菌炉房内及灭菌室外空气中EO质量浓度分别为0.08 mg/m~3和<0.01mg/m~3;在灭菌完后打开炉门至处理灭菌包完毕过程中,灭菌操作员EO接触量为0.94 mg/m~3,检测灭菌房内空气中EO残留量达到2.33 mg/m~3;在灭菌后抽风30 min后,检测灭菌包内EO残留量为133.59 mg/m~3;在灭菌后抽风2 h后,检测灭菌包内EO残留量为40.36 mg/m~3。结论 EO在打开灭菌炉后及灭菌包中的残留量较高,应加强抽风,降低环境及物品中的EO残留。
Objective To monitor the EO residuals in the surrounding environment and its sterilized articles when the hospital uses ethylene oxide (EO) to sterilize and assess its harm. Methods The 3M EO gas sampling box was used to collect the residual EO in the environment and articles during the sterilization process and determined by gas chromatography. Results The mass concentration of EO in the sterilization chamber and in the outdoor air after sterilization was 0.08 mg / m ~ 3 and <0.01 mg / m ~ 3, respectively. After the sterilization, the oven door was opened to treat the sterilization package At the end of the process, the exposure of the sterilizing operator to EO was 0.94 mg / m ~ 3, and the residual amount of EO in the air inside the sterilizing room was 2.33 mg / m ~ 3. After 30 min of evacuation after sterilizing, The residual amount of EO was 133.59 mg / m ~ 3. After 2 h of ventilation after sterilization, the residual amount of EO in the sterilization package was 40.36 mg / m ~ 3. Conclusion The residual amount of EO after the sterilizing oven is opened and in the sterilizing bag is high. Efflux should be strengthened to reduce the EO residue in the environment and articles.