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目的探讨多发性硬化(MS)患者的临床特点,以利提高诊断的准确性。方法回顾性分析39例的MS的临床资料。结果 39例病前多有诱因(61.5%),首发症状多样,常见的神经系统症状为肢体无力、感觉障碍、视力障碍及尿便障碍。病变部位多累及大脑半球、视神经、脊髓及脑干等处。MRI、脑脊液及诱发电位可见相应改变。结论 MS临床表现复杂,综合临床症状、体征、影像学、脑脊液及诱发电位有助于提高诊断的准确性,从而有利于改善预后。
Objective To investigate the clinical features of patients with multiple sclerosis (MS) to improve the diagnostic accuracy. Methods The clinical data of 39 cases of MS were retrospectively analyzed. Results Thirty-nine patients had predisposing factors (61.5%). The first symptoms were diverse. Common neurological symptoms were limb weakness, sensory disturbance, visual impairment and urinary stool disorder. More lesions involving the cerebral hemisphere, optic nerve, spinal cord and brain stem and other places. MRI, cerebrospinal fluid and evoked potentials can be seen corresponding changes. Conclusion The clinical manifestation of MS is complicated. The clinical symptoms, signs, imaging, cerebrospinal fluid and evoked potentials are helpful to improve the accuracy of diagnosis and improve the prognosis.