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目的:探讨与脑动静脉畸形(AVM)出血相关的临床及血管影像学特征,以期对脑AVM的出血倾向作出评价和预测。方法:应用Cox回归模型,对59例脑AVM进行出血危险因素的单因素及多因素分析。结果:59例脑AVM中,观察期内出血48例(占81%),年平均出血率为2%;病灶大小、供应动脉支数以及引流静脉支数是决定脑AVM出血倾向最重要的危险因素;小型AVM、多支动脉供应的AVM以及仅有单支静脉引流的AVM最易破裂出血。结论:建议脑血管造影时着重对此三项指标进行描述;对于出血风险较大的脑AVM应及早治疗。
Objective: To investigate the clinical and vascular imaging features related to cerebral AVM hemorrhage in order to evaluate and predict the bleeding tendency of brain AVM. Methods: Cox regression model was used to analyze the risk factors of bleeding in 59 cases of brain AVM by single factor and multivariate analysis. Results: In 59 cases of brain AVM, 48 cases (81%) had hemorrhage during the observation period and the average annual bleeding rate was 2%. The size of the lesion, the number of arterial feeding branches and the number of drainage veins were the most important risk factors ; Mini-AVMs, multi-vessel AVMs, and AVMs with single-vessel venous drainage are most vulnerable to rupture. Conclusion: It is suggested that these three indexes should be described emphatically in cerebral angiography. Brain AVM with high risk of bleeding should be treated as soon as possible.