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目的：探讨阻塞性睡眠呼吸暂停综合征(OSAS)与冠心病(CHD)发生、发展的关系。方法：通过使用多导睡眠仪对38例单纯OSAS患者、22例CHD并发OSAS患者进行氧减饱和度指数(ODI)监测分析。结果：CHD并发OSAS组的ODI最高为50.55±18.25，较OSAS组(38.65±14.28)明显增高(P＜0.05)，且与呼吸紊乱指数呈明显的正相关(P＜0.01)。结论：OSAS并发CHD组夜间缺氧程度最重、最频繁，OSAS患者CHD的发生可能与长期低氧有关。“,”Objective:To study the relation between the obstructive sleepapnea syndrome (OSAS) and coronary heart disease.Although there was some study, the exact mechanism about how the former develops to the latter was not completely known.Method:This study monitored 38 patients with simple OSAS and 22 OSAS patients complicated with coronary heart disease by analyzing their oxygen desaturation index (ODI) and apnea/hypopnea index (AHI).Result:The study explored that the ODI of the patients complicated with coronary heart disease was 50.55±18.25 ,which was greater than that (38.65±14.28) of the OSAS patients (P＜0.05).In addition,there was a significant positive correlation (r=0.451,P＜0.01) between ODI and AHI.Conclusion:Hypoxia of the OSAS patients complicated with coronary heart disease is most serious and frequent during sleeping.The occurrence of coronary heart disease in SOAS patients may result from long term hypoxia.