论文部分内容阅读
临床实践表明,使用抗菌药物后,个体的激素分泌、药效发挥、血药浓度及代谢周期等均会发生变化,因此应该在治疗的过程中,适当调整用药方式,以减少不良反应,保证药物的作用效果。世界卫生组织对临床抗菌药物的应用问题做出了明确的要求,表明合理掌握用药时间及间隔是用药的关键[1],应当引起充分的重视[2-3]。本文结合临床实际,对抗菌药物的作用特点,重点对用药时间进行总结,如下。1抗菌药物的药物代谢动力学(PK)/药物效应动力学(PD)、
Clinical practice shows that the use of antimicrobial agents, the individual hormone secretion, drug efficacy, blood concentration and metabolic cycles and so will change, it should be in the course of treatment, the appropriate medication to reduce adverse reactions to ensure that drugs The effect of. The World Health Organization made clear requirements on the application of clinical antimicrobial drugs, indicating that reasonable control of medication time and interval is the key to medication [1], which deserves full attention [2-3]. In this paper, clinical practice, the role of antibacterial drugs, focusing on the treatment time are summarized as follows. 1 Antimicrobial Pharmacokinetic (PK) / Pharmacodynamic (PD),