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为了解黑龙江省婴幼儿b型流行性感冒 (流感 )嗜血杆菌 (Hib)的感染状况 ,对哈尔滨、大庆、齐齐哈尔、佳木斯、鸡西、牡丹江6个市的 0～ 48月龄婴幼儿共 3 0 0份血清 ,用放射免疫方法进行了流感嗜血杆菌多糖 (Hib -PRP)抗体水平的监测。结果显示 :该人群抗体阳性率平均为 42 0 0 % ,其中男性为 3 6 94% ,女性为 47 5 5 % ;Hib -PRP抗体几何平均滴度 (GMT)为 0 18μg/ml。Hib-PRP抗体的年龄别分布是 :出生后抗体稍高 ,4～ 6月龄降至最低 ,8月龄后抗体阳性率和GMT随年龄增长而逐渐增高。按城市分 ,Hib -PRP抗体阳性率和GMT最高的是哈尔滨 ,其次为大庆、鸡西、牡丹江 ,最低的是齐齐哈尔、佳木斯。按采样地可分为医院组、城镇组和农村组 ,婴幼儿Hib -PRP抗体水平以医院组的明显高于城镇组 ,城镇组明显高于农村组。
In order to understand the infection status of influenza B (Hib) in infants and young children in Heilongjiang Province, a total of 30 children aged 0-48 months in Harbin, Daqing, Qiqihar, Jiamusi, Jixi and Mudanjiang 0 serums were detected by radioimmunoassay Haemophilus influenzae polysaccharide (Hib-PRP) antibody levels were monitored. The results showed that the antibody positive rate of this population averaged 42 0%, of which 3694% were males and 47.55% were females; the geometric mean titer (GMT) of Hib-PRP antibody was 0 18μg / ml. The age-specific distribution of Hib-PRP antibody was as follows: the antibody after birth was slightly higher, and the antibody level was lowest after 4 to 6 months. The antibody positive rate and GMT gradually increased with age after 8 months of age. By city, Hib-PRP antibody positive rate and the highest GMT is Harbin, followed by Daqing, Jixi, Mudanjiang, the lowest is Qiqihar, Jiamusi. By sampling can be divided into hospital group, urban group and rural group, infant Hib-PRP antibody levels in hospital group was significantly higher than the urban group, the urban group was significantly higher than the rural group.