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目的:探讨采用FoLey导尿管联合缩宫素用于足月妊娠促宫颈成熟和引产的有效性和安全性。方法:选取2018年1月至2019年2月来淮南市妇幼保健院就诊的有引产指征的足月初产妇90例作为研究对象，以区组随机化方法(以入院时间)分为观察组和对照组(各45例)。观察组产妇给予FoLey导尿管联合缩宫素引产，对照组产妇给予单纯缩宫素引产。比较两组产妇干预前后宫颈Bishop评分、治疗的总有效率和不良妊娠结局情况。结果:两组产妇干预后宫颈Bishop评分显著高于干预前[(8.62±1.25)分比(4.56±0.85)分，(7.09±1.13)分比(4.60±0.86)分]，且观察组产妇干预后宫颈Bishop评分显著高于对照组[(8.62±1.25)分比(7.09±1.13)分](n t＝6.091，n P<0.05)；观察组治疗总有效率显著高于对照组(97.78%比86.67%)(χn 2＝3.873，n P＝0.049)；观察组不良妊娠结局发生率显著低于对照组(4.44%比17.78%)(χn 2＝4.050，n P＝0.044)。n 结论:FoLey导尿管联合缩宫素对足月妊娠促宫颈成熟和引产疗效显著，不良妊娠结局发生率低，安全、有效。“,”Objective:To study the effectiveness and safety of FoLey catheter combined with oxytocin for full-term pregnancy promoting cervical maturation and labor induction.Methods:From January 2018 to February 2019, 90 cases of full-term primiparous women with induced labor indications in the Maternal and Child Health Hospital of Huainan were selected in the study.All cases were divided into observation group and control group(45 cases/group) by blocked randomization(admission time as a cooperating factor). The observation group was applied FoLey catheter oxytocin induction, the control group was applied oxytocin induction.The cervical Bishop scores before and after intervention, total effective rate of treatment and adverse pregnancy outcomes were compared between the two groups.Results:After intervention, the cervical Bishop scores of the two groups were significantly increased compared with before intervention [(8.62±1.25)points vs.(4.56±0.85)points, (7.09±1.13)points vs.(4.60±0.86)points], and the cervical Bishop score of the observation group was significantly higher than that of the control group after intervention [(8.62±1.25)points vs.(7.09±1.13)points] (n t=6.091, n P<0.05). The total effective rate of the observation group was significantly higher than that of the control group (97.78% vs.86.67% )(χn 2=3.873, n P=0.049). The incidence of adverse pregnancy in the observation group was significantly lower than that in the control group (4.44% vs.17.78%) (χn 2=4.050, n P=0.044).n Conclusion:FoLey catheter combined with oxytocin has significant effects on promoting cervical maturity and labor induction during full-term pregnancy.The incidence of adverse pregnancy is low, it is safe and effective.