论文部分内容阅读
目的：探讨新诊断2型糖尿病合并冠心病患者血糖、血脂、糖化血红蛋白（HbA1c）特点。方法选取38例新诊断2型糖尿病合并冠心病患者，并以37例单纯新诊断2型糖尿病患者，28例单纯冠心病患者以及37名健康对照进行研究。血糖采用葡萄糖氧化酶法，血脂分析采用酶法，HbA1c测定方法为离子交换高效液相色谱（HPLC）法。结果新诊断2型糖尿病合并冠心病患者HbA1c、Lp(a)明显高于其他三组（P＜0.01），FPG、LDL-C、TC和TG较冠心病组和对照组差异有统计学意义（P＜0.01）。新诊断2型糖尿病组FPG、HbA1c、TC和TG较冠心病组和对照组差异有统计学意义（P＜0.01）， Lp(a)较冠心病组差异有统计学意义（P＜0.01），LDL-C较对照组差异有统计学意义（P＜0.01）。冠心病组年龄、Lp(a)和LDL-C较对照组差异有统计学意义（P＜0.01）。结论新诊断2型糖尿病患者在诊断初期就应重视血脂谱的筛查。“,”Objective To investigate the clinical significance of blood glucose, blood lipid, glycosylated hemoglobin (HbA1c) in patients with newly diagnosed type 2 diabetes mellitus complicated with coronary heart disease. Methods 38 patients with newly diagnosed type 2 diabetes mellitus complicated with coronary heart disease (group A), 37 patients with type 2 diabetes mellitus (group B), 28 patients with coronary heart disease (group C) and 37 healthy controls (group D) were studied, blood glucose using glucose oxidase method, lipid analysis using enzyme method, HbA1c by ion exchange high performance liquid chromatographic method (HPLC). Results In group A, HbA1c, Lp(a) was higher than that of the other three groups (P<0.01), FPG, LDL-C, TC and TG have significant difference compared with group C and group D (P<0.01). In group B, FPG, HbA1c, TC and TG have significant difference compared with group C and group D (P<0.01), Lp(a) have significant difference compared with group C (P<0.01), LDL-C have significant difference compared with group D (P<0.01). In group C, age, Lp(a) and LDL-C have significant difference compared with group D (P<0.01). Conclusion After diagnosis, we should pay more attention early to screening blood lipid profile in the newly diagnosed type 2 diabetes patients.