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目的:分析探讨胃肠间质瘤(GIST)的临床病理学特征,为临床治疗提供更加可靠的参考。方法:对2013年2月至2013年12月期间在我院就诊的34例胃肠间质瘤进行常规病理及免疫组化,对CD117,CD34,SMA,S-100染色特点进行分析。结果:胃肠间质瘤主要分布在胃和小肠。34例中良性21例,低度恶性8例,恶性5例。胃肠间质瘤中有梭形细胞和上皮样细胞组成。免疫组化标记:肿瘤细胞以CD117和CD34阳性为主。结论:CD117,CD34标记阳性对胃肠间质瘤的诊断具有重要价值。
Objective: To analyze the clinical and pathological features of gastrointestinal stromal tumors (GISTs) and provide a more reliable reference for clinical treatment. Methods: Totally 34 cases of gastrointestinal stromal tumors treated in our hospital from February 2013 to December 2013 were routinely histopathologically and immunohistochemically analyzed for CD117, CD34, SMA and S-100 staining. Results: GISTs mainly distributed in the stomach and small intestine. Among the 34 cases, 21 were benign, 8 were low-grade and 5 were malignant. Gastrointestinal stromal tumors in spindle cells and epithelial cells. Immunohistochemistry: Tumor cells are predominantly CD117 and CD34 positive. Conclusion: Positive staining of CD117 and CD34 is of great value in the diagnosis of gastrointestinal stromal tumors.