目的　报告 6例罕见的与脑神经主干无关的颅内神经鞘瘤 ,结合文献以讨论其组织发生及临床特征和预后。方法　回顾性地分析 6例与脑神经主干无关的颅内神经鞘瘤。结果　 6例患者中 ,男 3例 ,女 3例 ,平均年龄 2 8岁 ( 10～ 5 4岁 )。肿瘤分别位于前颅窝底、蝶骨嵴内侧、枕大孔区和脑干、下丘脑及顶叶内 ,均经手术和病理证实。结论　与脑神经主干无关的颅内神经鞘瘤好发于儿童和年轻人。临床表现取决于肿瘤部位、大小及是否合并出血。如能安全地全切除肿瘤 ,预后良好。但其组织发生仍是一个谜 Objective To report 6 rare cases of intracranial schwannoma unrelated to cranial nerve trochanter, and to review the histological and clinical features and prognosis of these cases. Methods Six cases of intracranial schwannoma unrelated to cranial nerve trunk were analyzed retrospectively. Results 6 patients, 3 males and 3 females, mean age 28 years (10 ~ 54 years old). Tumors were located in the anterior cranial fossa, sphenoid ridge medial foramen magnum and brain stem, hypothalamus and parietal lobe, were confirmed by surgery and pathology. Conclusion The intracranial schwannoma which has nothing to do with the main nerve of the brain occurs in children and young people. Clinical manifestations depend on the location of the tumor, its size, and whether or not bleeding is associated with it. If the tumor can be safely removed, the prognosis is good. But its organization is still a mystery