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乙肝表面抗原无症状携带者及慢迁肝者定点定群于4年后观察HBsAg转阴率为12.15%,10年后转阴率为21.92%,其中携带者4年后HBsAg转阴率为16.90%,10年后转阴率24.00%。慢迁肝者4年后转阴率2.78%,10年后转阴率17.39%。健康配对者4年后HBsAg阳转率5.66%;10年后阳转率6.67%。原HBeAg阳性者4年后有62.07%转阴,10年后有40.00%转阴。原阴性者有34.48%转阳,持续10年HBsAg阳性者其抗-HBe有40.35%呈阴性,高滴度HBsAg伴HBeAg阳性者HBsAg转阴率较低。携带者10年后30%演变为慢迁肝及慢活肝,而原慢迁肝者有26.0%病情无改变,56.52%表面抗原持续阳性。
Hepatitis B surface antigen asymptomatic carriers and slow-moving liver fixed-point colonization in 4 years after the observed HBsAg negative rate was 12.15%, 10 years after the negative rate was 21.92%, of which 4 years after carrier HBsAg negative rate of 16.90 %, 10 years after the negative rate of 24.00%. 4 years after the slow transfer of liver conversion rate of 2.78%, 10 years after the negative rate of 17.39%. Health matched 4 years after HBsAg positive conversion rate of 5.66%; 10 years after the positive conversion rate of 6.67%. The original HBeAg positive 4 years after 62.07% negative, 10 years after 40.00% negative. 34.48% of patients with positive negative had positive conversion of HBsAg for 10 years. The anti-HBe was 40.35% negative while the high-titer HBsAg and HBeAg-positive patients had lower HBsAg negative rate. Carriers 30% 10 years later evolved into slowly moving liver and slow living liver, while the original chronic liver were 26.0% unchanged, 56.52% of the surface antigens continued to be positive.