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目的探讨相对运动强度和绝对运动强度对血清酶活性变化的影响。实验方法受试者为急性心肌梗塞康复病人(PMIP)和正常人(HS) ,实验前后测定了他们血清乳酸脱氢酶(L DH)、乳酸脱氢酶同工酶1(L DH- 1)、肌酸激酶(CK)、肌酸激酶亚单位MB(CK- MB)活性。结果两组受试者运动前酶的活性均无显著差异(P>0 .0 5 ) ;实验中,PMIP与HS的相对强度分别为最大心率的85 .1%、86 .0 % (P>0 .0 5 ) ,绝对强度分别为跑台等级的5 .3与6 .3(P<0 .0 5 ) ,PMIP与HS运动后即刻酶活性与运动前相比均有显著上升(P<0 .0 5 ) ,但两组间无显著差异(P>0 .0 5 ) ,2 4 h后HS组的酶活性基本恢复到运动前水平,但PMIP组仍高于运动前水平。结论运动后酶活性上升的幅度与运动所达到的相对强度有关;强度达85 % HRmax的运动能引起血清酶活性的升高,但此时L DH- 1/L DH和CK- MB/CK的比值与运动前相比无明显变化;如果PMIP的康复运动量等同于测试中的运动量,他们第2天似应停止活动以便能够得到充分的恢复。
Objective To investigate the effects of relative exercise intensity and absolute exercise intensity on changes of serum enzyme activities. The experimental subjects were acute myocardial infarction rehabilitation patients (PMIP) and normal subjects (HS). Their serum levels of lactate dehydrogenase (L DH), lactate dehydrogenase isoenzyme 1 (L DH-1) , Creatine kinase (CK) and creatine kinase subunit MB (CK-MB) activity. Results There was no significant difference in the activity of enzymes between the two groups before exercise (P> 0.05). The relative intensities of PMIP and HS were 85.1% and 86.0% respectively (P> 0.05). The absolute intensities were 5.3 and 6.3 (P <0.05) respectively at the treadmill level. The enzyme activity immediately after exercise was significantly higher than that before exercise (P < 0.05), but there was no significant difference between the two groups (P> 0.05). After 24 hours, the enzyme activity of HS group returned to pre-exercise level, but PMIP group was still higher than pre-exercise level. Conclusion The increase of exercise activity after exercise is related to the relative intensity of exercise. Exercise with 85% HRmax can induce the increase of serum enzyme activity, but at this time, L DH-1 / L DH and CK-MB / CK There was no significant change in the ratio compared with that before exercise; if PMIP was equal to the amount of exercise exercised during the test, they should probably stop exercising on day 2 so that adequate recovery could be achieved.