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目的:观察中西医结合治疗青光眼视神经萎缩的临床疗效。方法:60例青光眼视神经萎缩患者,随机分为2组,各30例。对照组采用常规西药治疗;观察组在对照组治疗基础上联合益肝复明汤治疗。治疗1月。比较2组临床疗效、视力、视野及图形视觉诱发电位(VEP)等指标。结果:总有效率观察组90.0%,对照组76.7%,2组比较,差异有统计学意义(P<0.05)。2组治疗后平均光敏度、平均缺损均有改善,与本组治疗前比较,差异有统计学意义(P<0.05);观察组各项指标均好于对照组,与对照组比较,差异有统计学意义(P<0.05)。2组治疗前视觉诱发电位(VEP)及眼压水平比较,差异无统计学意义(P>0.05);2组治疗后各项指标均有改善,与本组治疗前比较,差异有统计学意义(P<0.05);观察组治疗后视觉诱发电位AN75、LN75、AP100、AN135、LN135,显著高于对照组(P<0.05),LP100及眼压显著低于对照组,与对照组比较,差异有统计学意义(P<0.05)。结论:常规西药联合益肝复明汤治疗青光眼视神经萎缩,临床疗效显著,值得推广应用。
Objective: To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of glaucomatous optic atrophy. Methods: Sixty patients with glaucomatous optic atrophy were randomly divided into two groups (n = 30 in each group). The control group was treated with conventional western medicine. The observation group was treated with Yifu Fu Ming Tang on the basis of the control group. Treatment of January. The clinical efficacy, visual acuity, visual field and visual evoked potentials (VEP) were compared between the two groups. Results: The total effective rate was 90.0% in the observation group and 76.7% in the control group. There was significant difference between the two groups (P <0.05). The average photosensitivity and mean defect of two groups were improved after treatment, which were significantly different from those of the control group before treatment (P <0.05). The indexes in the observation group were better than those in the control group Statistical significance (P <0.05). There were no significant differences in VEP and IOP before treatment between the two groups (P> 0.05). After treatment, the indexes in both groups improved, and the difference was statistically significant (P <0.05). The visual evoked potentials AN75, LN75, AP100, AN135 and LN135 in the observation group were significantly higher than those in the control group (P <0.05), LP100 and intraocular pressure were significantly lower than those in the control group There was statistical significance (P <0.05). Conclusion: The conventional western medicine and Yifeng Fu Ming Tang treatment of glaucomatous optic atrophy, clinical significant effect, it is worth promoting application.