利用小鼠JB6细胞和分子克隆技术，湖南医科大学肿瘤研究所成功地从中国人鼻咽癌细胞珠CNE中克隆出恶性转化基因Tx。Tx基因在DNA杂交水平与Ha－ras、Ki－ras、及N－ras瘤基因以及src、myb、jun、fos、raf、int－2等无同源，将该基因转染至受体细胞JB6C141中能引起细胞转化，从而 Using mouse JB6 cells and molecular cloning technology, the Institute of Oncology of Hunan Medical University successfully cloned the gene Tx from Chinese CNE cell beads CNE. The Tx gene was not homologous to Ha-ras, Ki-ras, and N-ras tumor genes and src, myb, jun, fos, raf and int-2 at the level of DNA hybridization, and the gene was transfected into the recipient cell line JB6C141 Can cause cell transformation, thus