论文部分内容阅读
目的探讨特发性颅内压增高综合征(idiopathic intracranial hypertension,IIH)与颅内静脉窦病变的相关性。方法回顾性分析2004年-2008年北京市海淀医院及北京同仁医院收治的36例临床疑诊IIH患者的临床表现、影像学表现及血栓危险因素等临床资料。结果本组36例均为亚急性发病。首发症状视力障碍29例,头痛7例。伴随症状包括,波动性颅鸣1例(2.8%),眼胀痛2例(5.6%),头晕4例(11.1%),外展神经麻痹4例(11.1%)。按脑血管造影(DSA)结果分3组,颅内静脉窦闭塞15例(41.7%),狭窄组11例(30.5%),正常组10例(27.8%)。3组患者中有血栓危险因素者分别占80%、45.4%、30%,闭塞组与狭窄组和正常组之间比较均有显著性差异(P<0.05)。结论IIH患者静脉窦狭窄发生率高,静脉窦闭塞与血栓危险因素相关。
Objective To investigate the relationship between idiopathic intracranial hypertension (IIH) and intracranial sinus disease. Methods The clinical data, imaging findings and thrombotic risk factors of 36 suspected IIH patients admitted to Beijing Haidian Hospital and Beijing Tongren Hospital from 2004 to 2008 were retrospectively analyzed. Results The group of 36 cases were subacute disease. The first symptom of visual impairment in 29 cases, headache in 7 cases. The accompanying symptoms included 1 case of fluctuating cranial stenosis (2.8%), 2 cases of ocular pain (5.6%), 4 cases of dizziness (11.1%) and 4 cases of abducent nerve palsy (11.1%). The results of cerebral angiography (DSA) were divided into 3 groups, 15 cases (41.7%) of intracranial venous sinus occlusion, 11 cases (30.5%) of stenosis group and 10 cases (27.8%) of normal group. The risk factors for thrombosis were 80%, 45.4% and 30% in the three groups, respectively. There was significant difference between the occlusion group and the stenosis group and the normal group (P <0.05). Conclusions The incidence of sinus stenosis in patients with IIH is high, and the occlusion of sinus and related risk factors of thrombosis.