[氨基糖甙类抗菌素(Aminoglycoside Antibiotics)] 最主要的耳毒性药物是链霉素[基]族的各种抗菌素(Hawkins,1959),这些药物在微生物学、药物学和毒性上,彼此密切相关。多年来注射链霉素、双氢链霉素、新霉素、紫霉素、沙发霉素(framycetin)、万古霉素、卡那霉素等均被认为、疑为对迷路有不同程度的毒性(Leach,1962)。最近又加上庆大霉素、capreomycin和tobramycin。 [Aminoglycoside Antibiotics] The main ototoxic drug is streptomycin [group] of various antibiotics (Hawkins, 1959), which are closely related to each other in microbiology, pharmacology and toxicity . Streptomycin, dihydrostreptomycin, neomycin, viomycin, framycetin, vancomycin, kanamycin, etc. are thought to have been suspected for some years to have varying degrees of toxicity (Leach, 1962). Recently added gentamicin, capreomycin and tobramycin.