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目的探讨肿瘤发生在左大肠和右大肠时Ⅱ期大肠癌术后化疗患者肿瘤标志物癌胚抗原(CEA)表达是否存在差异。方法对近10年中山大学附属肿瘤医院217例临床Ⅱ期大肠癌术后化疗患者资料进行回顾性分析。结果左大肠癌患者89例(41%),右大肠癌患者128例(59%)。CEA左、右侧的阴、阳性率比较,差异有统计学意义(P=0.029),发病年龄比较,差异有统计学意义(P=0.005)。结论临床Ⅱ期左侧大肠癌患者CEA阳性率低于右侧。
Objective To investigate whether tumor-associated carcinoembryonic antigen (CEA) expression in patients with stage Ⅱ colorectal cancer after surgery in the left and right large intestine is different. Methods Retrospective analysis of 217 cases of clinical stage Ⅱ colorectal cancer patients after chemotherapy in Sun Yat-sen Affiliated Tumor Hospital in recent 10 years. Results 89 patients (41%) had left colorectal cancer and 128 patients (59%) had right colorectal cancer. CEA left and right side of the positive and negative rates, the difference was statistically significant (P = 0.029), age of onset, the difference was statistically significant (P = 0.005). Conclusions The positive rate of CEA in patients with stage Ⅱ colorectal cancer is lower than that in right side.