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目的:评价甲硝唑对预防剖宫产患者术后感染的疗效。方法:选取2014年—2016年3月间收治的需剖宫产的产妇96例,采用随机分组法将其分为治疗组和对照组,每组48例;治疗组患者剖宫产术后给予甲硝唑液无菌纱布擦拭宫腔以及冲洗宫腔预防,对照组患者术后给予0.9%氯化钠注射液擦拭宫腔以及冲洗宫腔。结果:治疗组产妇用药后术后腹壁切口感染率为2.08%和术后患病率为4.17%,明显低于对照组为10.42%和1 8.75%(P<0.05);治疗组产妇用药后WBC、ESR、CRP测得值均明显低于对照组(P<0.05)。结论:剖宫产术后产妇预防用甲硝唑可有效预防术后切口感染,疗效较为确切。
Objective: To evaluate the efficacy of metronidazole in preventing postoperative infection in patients with cesarean section. Methods: Ninety-six maternal women undergoing cesarean section were enrolled between 2014 and March 2016. The patients were divided into treatment group and control group with 48 cases in each group. The patients in treatment group were given cesarean section Metronidazole sterile gauze wipe the uterine cavity and irrigation uterine prophylaxis, the control group of patients given 0.9% sodium chloride injection wipe the uterine cavity and rinse the uterine cavity. Results: The infection rate of abdominal incision and the postoperative morbidity in the treatment group were 2.08% and 4.17%, respectively, which were significantly lower than those in the control group (10.42% vs 1. 8.75%, P <0.05). The WBC , ESR, CRP were significantly lower than the control group (P <0.05). CONCLUSION: Metronidazole for preventing maternal postpartum cesarean section can effectively prevent incision infection after curative effect.