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目的：观察利巴韦林注射液治疗急性上呼吸道感染的临床效果。方法将110例上呼吸道感染患者随机分为观察组和对照组各55例。观察组患者采用利巴韦林注射液进行治疗，对照组患者采用炎琥宁进行治疗。对比2组临床疗效、症状改善时间、住院时间及不良反应发生情况和安全性评分。结果观察组治疗总有效率及治疗的安全性评分均高于对照组，不良反应发生率低于对照组，症状改善时间及住院时间短于对照组（P＜0．05）。结论利巴韦林注射液治疗急性上呼吸道感染疗效显著，值得临床广泛推广应用。“,”Objective To observe the clinical effect of ribavirin in acute respiratory infection .Methods 110 cases patients with upper respiratory tract infection were randomly divided into observation group and control group ,each of 55 cases. Observation were treated by ribavirin injection .Control group were treated by yanhuning .After treatment,compared the clinical effect,symptom improve time,hospitalization time and adverse eventsecurity rating of 2 groups.Results The total efficiency and security rating of observation group were higher than that of control group ,the rate of adverse reactions of observation group was lower than that of control group ,the symptom improve time ,hospitalization time of observation group were shorter than that of control group,the difference was statistically significant (P<0.05).Conclusion The clinical effect observation of ribavirin in acute respiratory infection has an good effect ,worthy of clinical application .