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苦参是具有清热燥湿、杀虫功效的中药，治疗恶性肿瘤有效。其主要成分为生物碱，如苦参碱（ｍａｔｒｉｎｅ，Ｍａ）和氧化苦参碱（ｏｘｙｍａｔｒｉｎｅ），能杀伤肿瘤细胞，诱导ＳＭＭＣ－７７２１细胞和ＨＬ－６０细胞分化［１，２］。本组研究旨在探讨苦参碱的抗癌作用是否
Sophora flavescens is a traditional Chinese medicine that has heat-clearing, dampness and insecticidal effects and is effective in the treatment of malignant tumors. Its main components are alkaloids, such as matrine (Ma) and oxymatrine, which can kill tumor cells and induce differentiation of SMMC-7721 cells and HL-60 cells [1, 2]. This study was designed to investigate whether the anti-cancer effect of matrine is