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目的探讨B型钠尿肽(BNP)的临床应用价值。方法选择平顶山煤业集团总医院住院治疗的患者,分为CHF组86例、无CHF发生组(对照组)85例。采用免疫荧光法测定血浆BNP浓度。结果 CHF组血浆BNP为(395±260)pg/ml;对照组BNP为(15±13)pg/ml。两组对照比较P<0.01;CHF组治疗前后对比(P<0.01),差异均有统计学意义。结论 BNP是反映早期心功能受损的敏感指标及治疗效果观测指标。
Objective To investigate the clinical value of B-type natriuretic peptide (BNP). Methods Patients in Pingdingshan General Hospital of Chinese Medicine were selected and divided into CHF group (n = 86) and CHF group (n = 85). Plasma BNP concentration was measured by immunofluorescence. Results Plasma BNP was (395 ± 260) pg / ml in CHF group and (15 ± 13) pg / ml in control group. P <0.01 in the two groups; compared before and after treatment in the CHF group (P <0.01), the differences were statistically significant. Conclusion BNP is a sensitive indicator of early impaired cardiac function and an indicator of the therapeutic effect.