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目的探讨观察多形态梅毒疹合并非淋菌性尿道炎的临床诊断及治疗方法,总结其临床疗效。方法选取我院2009年10月~2010年12月期间收治的多形态梅毒疹合并非淋菌性尿道炎27例,治疗12个月后观察其临床症状与治疗效果的分析。结果所有病例经治疗后均有所好转,随访12个月无1例复发,27例患者在治疗中使用阿奇霉素治疗非淋菌性尿道炎效果明显,治疗多形态梅毒疹无效,在改用苄星青霉素后皮损消退,快速血清反应素环状卡片试验(RPR)滴度下降,27例患者经USR测定,其中12例患者于治疗后3个月转阴。10例于6个月转阴,5例于9个月转阴,12个月后无复发。结论阿奇霉素治疗非淋菌性尿道炎效果明显,治疗多形态梅毒疹无效,在改用苄星青霉素后皮损消退。
Objective To investigate the clinical diagnosis and treatment of multi-morphous syphilis combined with non-gonococcal urethritis and to summarize its clinical efficacy. Methods Select 27 cases of polymorphic syphilis combined with non-gonococcal urethritis admitted from October 2009 to December 2010 in our hospital. After 12 months of treatment, the clinical symptoms and treatment effects were analyzed. Results All cases were improved after treatment. There was no recurrence in 12 months after follow-up. 27 cases were treated with azithromycin in treatment of non-gonococcal urethritis, the effect is obvious, the treatment of polymorphic syphilis is ineffective, After the skin lesions subsided, the rapid serotonin ring card test (RPR) titer decreased, 27 patients were measured by USR, of which 12 patients turned negative 3 months after treatment. Ten patients were negative at 6 months, 5 were negative at 9 months, and no recurrence occurred 12 months later. Conclusion Azithromycin treatment of non-gonococcal urethritis effect is obvious, the treatment of polymorphic syphilis is invalid, after the switch to benzathine penicillin subsided.