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目的:探讨倍他乐克对急性心肌梗死(AMI)溶栓再通患者心肌保护作用。方法:AMI早期溶栓再通患者,随机分为两组,治疗组给予足量倍他乐克,对照组则只予常规倍他乐克治疗,然后比较两组的心肌激酶的峰值浓度、恢复正常时间,再梗及心律失常发生率,梗死面积及左室功能。结果:治疗组心肌激酶峰值浓度、时间,恢复正常时间,再梗及心律失常发生率、梗塞面积均低于对照组,心功能明显改善。结论:早期足量使用倍他乐克可改善AMI早期溶栓再通患者的预后。
Objective: To investigate the protective effect of Betaloc on myocardium after thrombolytic recanalization in acute myocardial infarction (AMI). Methods: The patients with AMI in the early thrombolytic recanalization were randomly divided into two groups. The treatment group was given enough Betaloc, while the control group only treated with metoprolol. The peak concentrations of myocardial kinase in the two groups were compared and recovered Normal time, restenosis and arrhythmia incidence, infarct size and left ventricular function. Results: The peak concentration of myocardial kinase, the time, the normal time of recovery, the incidence of recanalization and arrhythmia, the infarction area in the treatment group were lower than those in the control group, and the cardiac function improved significantly. CONCLUSIONS: Early adequate use of metoclopram improves the prognosis of patients receiving AMI in the early stage of thrombolysis.