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目的 了解湘西自治州少数民族地区小儿人群弓形虫感染情况。方法 选择本院儿科住院病人 5 2 9例 ,应用血清学ELISA方法检测弓形虫的特异性抗体IgG、IgM和循环抗原 (CAg)。结果 IgG阳性率 1 0 .0 2 % ,IgM阳性率 8.3 2 % ,CAg阳性率 0 .95 % ,IgG +IgM阳性率 1 1 .5 3 % ,IgM +CAg阳性率 1 .1 3 % ,IgG +IgM +CAg阳性率为 0 .3 8%。与动物有密切接触史的患儿感染率高于无密切接触史的患儿(P <0 .0 0 5 )。农村患儿感染率高于城市患儿 (P <0 .0 1 )。结论 本地区儿科临床病人弓形虫感染总感染率为 3 2 .3 3 % ,发现各类临床病人都有感染 ,单纯IgG阳性有治疗价值。
Objective To understand the prevalence of toxoplasma in pediatric population in minority areas of western Hunan Province. Methods A total of 529 inpatients were selected as pediatric inpatients. Serum ELISA was used to detect the specific antibodies IgG, IgM and CAg of Toxoplasma gondii. Results The positive rate of IgG was 10.2%, the positive rate of IgM was 8.3 2%, the positive rate of CAg was 0.95%, the positive rate of IgG + IgM was 11.33%, the positive rate of IgM + CAg was 1.13% + IgM + CAg positive rate of 0.38%. The infection rate in children with close contact with animals was higher than that in children without close contact history (P <0.05). The prevalence of children in rural areas was higher than that of urban children (P <0.01). Conclusion The total infection rate of Toxoplasma gondii in pediatric clinical patients in this area was 32.33%. It was found that all clinical patients had infection, and the positive value of IgG was positive.