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血小板来源于骨髓巨核细胞,它是血液中最小的无核细胞。血小板在体内有营养血管内皮细胞、止血、纤溶活性、参与炎症反应及免疫等多种作用。这些作用不仅取决于体内血小板的数量,更重要的是依靠血小板的粘附、聚集、释放和促凝等生理功能。血小板功能低下可导致出血,而其功能亢进与血栓形成,动脉粥样硬化及某些心脑血管疾病的重要关系,近年来已引起了多方面注意。本文将血小板功能及其检查方法,血小板与缺血性脑血管疾病(ICVD)的发病机理上的关系简述如下。
Platelets are derived from bone marrow megakaryocytes, which are the smallest non-nucleated cells in the bloodstream. Platelets in the body of nutrient vascular endothelial cells, hemostasis, fibrinolytic activity, involved in inflammation and immune and other effects. These effects depend not only on the number of platelets in the body, but more importantly on the physiological functions of platelets such as adhesion, aggregation, release and pro-coagulation. Platelet dysfunction can lead to bleeding, and its important function of hyperthyroidism and thrombosis, atherosclerosis and certain cardiovascular and cerebrovascular diseases, has attracted many attention in recent years. This article will platelet function and examination methods, platelet and ischemic cerebrovascular disease (ICVD) on the pathogenesis of the relationship as outlined below.